标记档案: ENCODE项目联盟

UCSC Genome Bioinformatics

一周的视频提示: UCSC基因组外显子的浏览器仅模式,en

球队在 UCSC基因组浏览器 continues to update their resources and offer new ways to find and visualize features of interest to researchers. One of the newer features is the “多区域” option. When it was first launched, I did a tip on how to use that, with some of the things that I noticed while I was testing it pre-launch. But now the folks at UCSC have their own video on the exon-only display that you might also find useful.

One of the things that is illustrated here is how the exon-only mode is handy to enhance your exploration of RNA-Seq data. It also uses a great 进行编码 data set as an example, and if you haven’t been using that collection it’s a good reminder of the kinds of things you can find in that resource still. And this extensive data set shows how much easier it is to look at different isoforms in the data in this new exon-only mode.

So have a look at this display option if you haven’t before, especially how it can help you to see transcript differences. 如果你不熟悉的 编码资料 that’s being used, you can also see our training on that which will help you to understand how to use that data and the filtering features that are also used in this video.

特别说明: I have updated the UCSC Intro slides to include the new Gateway strategies as well. So download those slides for the latest look.

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披露: UCSC Genome Browser tutorials are freely available because UCSC 赞助商 us to do training and outreach on the UCSC Genome Browser.

快速链接:

UCSC基因组浏览器: http://genome.ucsc.edu

UCSC Genome Browser training materials: http://openhelix.com/ucsc

进行编码: 銈://www.openhelix.com/ENCODE2

参考文献:

带动, 米, 科, 答:, 罗森布鲁姆, 光, 雷尼, 二, 赞助商, 二, Nejad, 体育, 李, 二, 学习, 光, Karolchik, 四, Hinrichs先生, 答:, 海特纳, 学, 硬, 河, Haeussler, 米, Guruvadoo, 属, 藤田, 体育, Eisenhart, 三, Diekhans, 米, 克劳森, 阁下, 卡斯帕, j的, 理发, 克, 豪斯勒速度, 四, 库恩, 河, & 肯特, 在. (2016). UCSC基因组浏览器数据库: 2016 更新 核酸研究, 44 (D1) 分类号: 10.1093/nar/gkv1275

ENCODE项目联盟 (2012). 一个集成的人类基因组中的DNA元件的百科全书 自然, 489 (7414), 57-74 分类号: 10.1038/nature11247