There are many tools at NCBI的, with a huge range of functions. 文学, 序列数据, 变化, 蛋白质结构, chemicals and bioassays, 多. It’s hard to keep track of what’s available. Their video tutorials are helping me to be aware of new tools, and new features within existing tools. 本周的周提示, we’ll look at their recent video for ProSplign. It’s a tool that will help you align protein information to genomic sequences.
虽然 基因组工作台 itself has been around for a while (we featured it as a tip it first in 2013), it is constantly underdevelopment, and new features are available regularly. And although this tip focuses on how to use the ProSplign piece, if you haven’t used it much it will help you to understand how a number of tools within the Workbench can be accessed. You can also see that Splign is available in the tool list–which is another NCBI tool for a similar type of process, but with mRNA sequences as the focus.
If you want to have a text-based type of walk-through instead, there is a page that will take you through the features (see the quick links below). And there are other videos that will help you to explore the Genome Workbench features as well–there’s a handy special playlist of just those 视频. Subscribe to their YouTube channel for notices of their new items.
Text-based tutorial page: https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial13/
卡普斯京, 华, Souvorov, 答：, Tatusova, 吨, & 李普曼, ð. (2008). Splign: algorithms for computing spliced alignments with identification of paralogs Biology Direct, 3 (1) 分类号: 10.1186/1745-6150-3-20
NCBI staff (2016). 国家生物技术信息中心的数据库资源 核酸研究, 44 (D1) 分类号: 10.1093/nar/gkv1290