Tag: GWAS

Tip of the Week: Human SNP-coexpression associations, SNPxGE2

8 February, 2012 (12:00) | Tip of the Week | By: Trey

Today’s tip is on a new database based on data from a single interesting paper, SNPxGE2. With a  large scale association study from HapMap data (269 individuals, 4 populations, over 500k SNPs and 15k expression profiles), the research reported: the computationally predicted human SNP-coexpression associations, that is, the differential co-expression between 2 genes is associated with the [...]

Are you wicked smart?

19 August, 2011 (11:41) | Genomics Research | By: Mary

Or, as it’s pronounced around my house: ah you wikked smaht? There’s a recruiting effort by the BGI (Beijing Genomics Institute–which is not limited to Beijing anymore) to obtain a collection of wicked smart people and analyze their DNA. They are looking for genes  for intelligence. I looked at the automatic criteria, and I’m not [...]

What’s the Answer? Open Thread (GWAS genotyping)

14 July, 2011 (08:00) | What's the Answer? | By: Trey

BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of the community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those questions and answers here in this [...]

Tip of the Week: Prioritizing Genes

6 July, 2011 (09:18) | Tip of the Week | By: Trey

Many types of experiments today return large lists of genes, association studies, expression arrays, linkage analysis and more. The researcher needs to determine which of those genes are of most interest and promising so the next step in the analysis is to prioritize the list and find the method to do so. There are a [...]

“What’s the Answer” Thread

3 February, 2011 (08:57) | What's the Answer? | By: Trey

BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of the community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday* we will be highlighting one of those questions and answers here in this [...]

Tip of the Week: RepTar, a database of miRNA target sites

15 December, 2010 (01:34) | Tip of the Week | By: Trey

microRNAs have become a rich source of research as they probably have a huge effect on gene expression and disease. The human genome may encode over 1,000 miRNAs that target over half of our genes. They might be implicated in a lot of common diseases (which not yet have been picked up in GWAS studies?). [...]

DNA Deniers

13 December, 2010 (10:05) | General Science | By: Mary

Wha? From Michael Pollan: Wha? Michael Pollan and his flock became all aerated the other day when Michael tweeted this tidbit. It links to a story with quite the title: The Great DNA Data Deficit: Are Genes for Disease a Mirage? Srsly. That’s what it says. What do I think this is? The second case [...]

Friday SNPpets

13 August, 2010 (09:00) | SNPpets | By: Mary

Welcome to our Friday feature link collection: SNPpets. During the week we come across a lot of links and reads that we think are interesting, but don’t make it to a blog post. Here they are for your enjoyment… RoBuST “has been developed as root and bulb plant community research platform for integrated analysis of [...]

Friday SNPpets

23 July, 2010 (08:46) | Genomics Research, Genomics Resource News, SNPpets | By: Mary

Welcome to our Friday feature link dump: SNPpets. During the week we come across a lot of links and reads that we think are interesting, but don’t make it to a blog post. Here they are for your enjoyment… Accessing SEED genome databases via web services, hat tip to Jonathan Eisen. [Mary] Galaxy team wants to [...]

Tip of the Week: GRAIL for prioritizing SNPs

9 December, 2009 (07:45) | Genomics Research, New Resource, Tip of the Week | By: Mary

Perusing my copy of Nature Genetics last week, I was flipping through the pages and noticed an unusual graphic.  I looked at it a little closer and was convinced it was one of the Spirographs that I used to make as a kid.  (Remember those? I always liked that….)  I looked a little bit closer [...]