19 May, 2008 (20:16) | Genomics Research | By: Trey
A paper published today in PLoS One reports on research that shows the feasibility of taking a gene or genomic region from an extinct species and inserting it into the genome of an extant species and resurrect the extinct species DNA function in the transgenic mice. The extinct species was the Tasmanian tiger or Thylacine [...]
Tags: evolution, genomes, MGI, mouse, plos one, tasmanian tiger, thylacine, transgenic, UCSC Genome Browser
13 May, 2008 (12:52) | General Science | By: Trey
I love my job, databases intersect with my personal interests often. “A blog around the clock” reports on a new open access Sleep Journal and a “Sleep Database.” As someone with sleep apnea (and whose CPAP machine changed his life), I am fascinated by the entire subject. So I’ll be keeping tabs on the journal, [...]
Tags: allen brain atlas, database, evolution, evolution of sleep, phylogeny of sleep, sleep, sleep apnea, sleep research society
9 May, 2008 (16:10) | General Science | By: Trey
That is what Platypus do, even as mammals . Two days ago the Platypus genome was published in Nature. So if you haven’t already read it, might be worth a skim at least. So, they aren’t model organisms and not a medically or agriculturally important animals (unless someone starts figuring out how to cook platypus [...]
Tags: evolution, genome, platypus, UCSC Genome Browser
10 March, 2008 (15:04) | General Science, Genomics Research | By: Trey
Dr. Eisen at UC Davis has started a new blog theme on his “Tree of Life” blog called “Open Evolution” (open access publications, open source programs, etc) and has started with open access journals. He has listed a few open access journals (and there’s a good discussion in the comments about the difference between ‘open [...]
Tags: databases, evolution, open access, open source, phylogenetics, phylogenomics, phylogeny
26 February, 2008 (16:46) | General Science, Genomics News | By: Trey
In 1993 I remember discovering the web. It wasn’t much longer after that I discovered the “Tree of Life (ToL).” I was studying for my Ph.D. in evolutionary biology and heard about it by word of mouth. Sometime in 1996 I found it on the web and was intrigued. It has grown since then, though [...]
Tags: databases, directories, encyclopedia of life, eol, evolution, genomes, species, tol, tree of life
Comments: 5
20 February, 2008 (00:23) | Tip of the Week | By: Trey
Today’s tip looks at one example of how to view the same genomic data across several databases simply by browsing. You can download the data from analysis tools and databases in several formats and use that in others, and someday we’ll do a tip on that. But today’s tips shows you that many databases link [...]
Tags: comparative genomics, darwin day, database formats, ensembl, evolution, UCSC Genome Browser, vista
30 January, 2008 (00:53) | Genomics Research, New Resource | By: Trey
I just finished reading this paper out this month in PNAS, “Specific expression of long noncoding RNAS.” From the looks of it, the paper has conjured up an interesting discussion in the science blogosphere surrounding the paper and the term “Junk DNA.” Before I get to that discussion, let me give a brief synopsis of [...]
Tags: evolution, genome, junk dna, NAR, ncRNA, noncode, transposons
Comments: 10
14 January, 2008 (17:12) | Genomics Research | By: Trey
I’ve been following a fascinating conversation about this paper: Recent acceleration of human adaptive evolution by John Hawks et al. In this paper the authors found that: Genomic surveys in humans identify a large amount of recent positive selection. Using the 3.9-million HapMap SNP dataset, we found that selection has accelerated greatly during the last [...]
Tags: adaptive, evolution, genome, hapmap, human, pnas, snps, UCSC Genome Browser, variation
4 January, 2008 (13:02) | General Science | By: Trey
You have some non-biologist colleagues (attorney? manager? programmer?) you need to get up to speed, or you need to brush up on some concepts yourself? A good place to start is this list from John Wilkins (Evolving Thoughts). It is a list of links to blog post across the blogosphere that explain and expound on various basic [...]
Tags: biology, education, evolution, tutorial
Comments: 2
31 December, 2007 (15:37) | Genomics Research, Genomics Resource News | By: Trey
I finally got around to reading last month’s Nature paper on the genomic sequence of 12 Drosophila species. In addition to being genomics research (which is my field now , it is also looking at 12 of the couple dozen species I studied for my Ph.D. (though I was only looking at the evolution of [...]
Tags: drosophila, ensembl, evolution, flybase, genome, genome browser, gramene, mapviewer, TAIR, UCSC Genome Browser
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