Well, as far as I can tell, read & do all the normal stuff for staying healthy (you know, all the stuff Mom used to say – wash your hands, drink plenty of liquids, eat right & get plenty of sleep.) I heard about swine flu as I woke up yesterday morning listening to NPR, [...]
For today’s tip, I would like to introduce you to the TDR Targets Database, which seeks “… to exploit the availability of diverse datasets to facilitate the identification and prioritization of drug targets in pathogens causing neglected diseases.” I found out about this database this past weekend as I was catching up on my [...]
Recently, we are learning a lot about the cold virus. The genomes of many have now been sequenced (that is a subscription-required Science report, you can read more about the report here). You can find more genomic information at the picornaviridae.com at the NCBI’s Entrez Genomes and some structural information at MMDB. (just a side [...]
One of the most common questions we get when we are out doing software training is: what do I do with a list of genes? People generate lists from all sorts of biomedical research forays: microarray results, database searches, literature searches, library screens, etc. The source doesn’t matter much–in the end people have this list [...]
The Comparative Toxicogenomics Database (or CTD) is an excellent database to find information on chemical-gene-disease interactions. It is a manually curated database of chemical-gene interactions, chemical-disease and gene-disease associations. At your fingertips you can find information about chemicals, interacting gnees, inferred diseases, pathways, references and news. It’s worth a look. And you can use Google [...]
(click either graphic to see the tip of the week movie) It’s not Halloween yet, but thought I’d get us started in the mood by introducing you to a database that has some obvious references to the movie “The Fly” (the 1958 version is the only really worth watching . Ok, so the database doesn’t [...]
We go through the thousands of resources and databases available online in our search to do tutorials we found many that are great resources but for one or more reasons we don’t or can’t do a tutorial for. Yet they are great resources. So, we occasionally do “Tip of the Week” on some, but even [...]
As genome-wide association studies (GWAS) become much more widespread and useful, the genome browsers are finding ways to incorporate these data and to allow you to view the published data or your own. The UCSC team has already developed a useful interface in their “Genome Graphs” tool which allows you to view and compare disease [...]
One of the things I’ve been thinking about lately are connections between genotype and phenotype – it is a topic in the news & I have been working on tutorials for the genotype-to-phenotype resources PhenomicDB & NCI’s dbGaP. Recently a friend notified of an article in Science featuring the PhysioNet – a resource intended to stimulate [...]
that was fun writing that title. A recent correspondence in Nature Genetics outlined some changes in the HuGE Navigator. This database has been available in some form since 2001. The basic purpose of the database is to… navigate and mine the growing scientific literature on human gene-disease associations and related data in human genome epidemiology. [...]
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