A few years ago I did a tip on the proteomic tools list available from the ExPASy site. You can still get to that list, but it is no longer being updated. Instead the entire ExPASy site has been updated and reorganized and is now the new Swiss Institute of Bioinformatics (SIB) Bioinformatics Resource Portal. In today’s tip I want to explore the updated site & show you a few of the new features.
ExPASy was created in 1993, and was one of the first resources online for biomedical research. It has been a great resource for years, and you can learn a lot about their history and goals from their original paper (referenced below). But they have also evolved. According to the ExPASy press release:
Eighteen years later, ExPASy is still an indispensable resource worldwide. Its transformation into a bioinformatics resource portal with the possibility to search for data in various interconnected fields such as proteomics, genomics, phylogeny, systems biology, evolution, drug design and imaging will allow
life science researchers to optimise their research activities through access to an enriched set of high-quality data.
The updated site allows researchers to access the SIB content using Visual Guidance, Categories, an alphabetized list or through querying the site. I’ll quickly show you most of these methods. Once you know how to search the ExPASy site, you’ll have a powerful access point for finding and querying over 120 SIB resources. OpenHelix has a huge respect for the resources that the SIB groups have created, and we have created tutorials on many of them including PROSITE, STRING, and UniProt. We also touch on many others in tutorials or tips, so if you’d like more details than are offered in the SIB resource documentation, use our search portal to see what we have on the resource. If there are SIB resources that you’d like to see us develop on, please comment and let us know – we’re always happy to add another useful resource to our international resource list, which currently includes thousands of resources.
Quick link to the SIB Bioinformatics Resource Portal: http://www.expasy.ch/
Gasteiger, E. (2003). ExPASy: the proteomics server for in-depth protein knowledge and analysis Nucleic Acids Research, 31 (13), 3784-3788 DOI: 10.1093/nar/gkg563