What’s the Answer? Open Thread (Orthology)

BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of the
community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those questions and answers here in this thread. You can ask questions in this thread, or you can always join in at BioStar.

Question of the week (it was much longer than below, but this is the crux of the matter):

I want to know which is the best tool if I want to find ortholog genes of all human genes in primates, mouse.

There were some great answers, all with great resources. The top rated one (one of the best rated answers I’ve seen), writes almost a review article in answer. It’s excellent. I’m having a difficult time distilling it down for this, he goes through lots of criteria and tools, but his last sentence is:

Human, other primates and mouse are well represented in MetaPhOrs (combining Ensembl and other DB predictions). Following the above reasoning, I would give it a try.