“What’s the Answer?” thread

BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of the community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those questions and answers here in this thread. You can ask questions in this thread, or you can always join in at BioStar.

BioStar Question of the Week:

How to retrieve human proteins sequence containing a given domain
I would like to know what is the best way to retrieve the human proteins sequences that contains a given domain (e.g. : FYVE). Thanks in advance for sharing your approach(es).  –Fred

Although there was no “selected” answer, this question drew several responses of ways to approach this. Some included code-based scripting solutions, but several of them offered ways to accomplish this with user interface tools at SMART, BioMart, Pfam, and UniProt.  (And by the way, our subscription package has tutorials for each of those tools that would help you to accomplish these things if you weren’t familiar with them.)

Explore the question and the suggested strategies here: http://biostar.stackexchange.com/questions/5862/how-to-retrieve-human-proteins-sequence-containing-a-given-domain