Gene phylogenies (as opposed to species phylogenies) can be very useful in determined gene function, history, orthology and paralogy predictions. PhylomeDB (link added!) is a database of gene phylogenies (or as they call them, Phylomes.. no end to the ‘omes is there? :). Currently there are over a dozen such phylomes from species like humans and yeast. The database allows you to obtain phylogenies of genes based on gene ID or BLAST, you can also get orthology predictions and alignments and more. Today’s tip is introducing you to the database.