Tip of the Week: Lists of genes–>Term Enrichment with GO
The question we probably hear the most from researchers is…what can I do with a giant list of genes to figure out what’s going on in there? And about once every 6 months this question comes across the Gene Ontology mailing list. This is followed by a flurry of developers who offer their cool tools for analysis purposes. There are actually quite a few different tools with different strategies out there–and they are designed for different purposes, and in this tip I’m going to use the Gene Ontology consortium’s GO Term Enrichment tool as a primary example, but I’ll also point you to a list of other tools to try out.