Tip of the week: SMART protein domain analysis
We find that many people are interested in learning more about the domains in their proteins of interest. A great tool to use to examine the domains, their architecture/organization, and their relationships is SMART, the Simple Modular Architecture Research Tool. It is developed and maintained by the Bork lab at EMBL (a source of many great tools). This appetizer movie may get you interested in examining your proteins of interest with the SMART analysis. We show you how to find hundreds of proteins with “transmembrane receptor” domains in about 3 minutes.
We have a complete tutorial on SMART that presents the information in much more detail.
Comments
Comment from Jing
Time September 30, 2008 at 12:43 PM
MFQIKLAVSLFILASLGAMVNAKKMVNCYYGTWAKYRTGNGNFEAENIDPFLCTHISYSFFGIDGASGRFKSLDTWLDMDTGLGMIRKTMQLKSKNPNLKILAVVGGWNEGSDKFSAMAADPHKRKAFIDSSLAFIKQYGFDGLDIDWEYPAQREGSSPRDKQNFVTLLKELKNALSPLNLELGIAVGASATTAAISYDIPNIAKYVDFINVMTYDFHNQATLSYNSPLKGQGENNVESAIKYWLNAGAPASKLIMGLAFYGRHFAYAQQPQAGAPQLGEGTPGPYTQQRGFLGYNEICQLKNSGYNFQFDNAHGVPYAYNGNQWIGFDDAKSIAMKVQLANTLNLGGAMVWSLESDDFRGECGEKYVLLNALNSALGGSSSWNPNPPQTVTTRKPSVVVTSAPVVSKPNAPAGCSSDGYFANQSDCNRFYQCSGGVRYEYNCAAGLHFDTVSLSCTWPGQANCGN
Comment from Mary
Time September 30, 2008 at 2:16 PM
Hi Jing–
I’m assuming you want this amino acid sequence analyzed for domains? You need to take it over to the SMART site and paste it right into their text box.
We don’t host any of the analysis software here. We only host the training materials 
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Time December 24, 2008 at 11:49 AM
[...] Mar. 19 Tip of the week: SMART protein domain analysis [...]
Comment from Mary
Time June 15, 2010 at 3:41 PM
Hi Anon–
I’m assuming that’s a protein sequence….You need to take it over to SMART and enter it in the box that says Sequence.
I just realized in our blog migration the movie didn’t make it. I’ll try to get that fixed.
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Time March 19, 2008 at 10:42 AM
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