Tip of the week: SMART protein domain analysis

We find that many people are interested in learning more about the domains in their proteins of interest. A great tool to use to examine the domains, their architecture/organization, and their relationships is SMART, the Simple Modular Architecture Research Tool. It is developed and maintained by the Bork lab at EMBL (a source of many great tools). This appetizer movie may get you interested in examining your proteins of interest with the SMART analysis. We show you how to find hundreds of proteins with “transmembrane receptor” domains in about 3 minutes.

We have a complete tutorial on SMART that presents the information in much more detail.

5 thoughts on “Tip of the week: SMART protein domain analysis

  1. Pingback: Protein Basics | The OpenHelix Blog

  2. Jing

    MFQIKLAVSLFILASLGAMVNAKKMVNCYYGTWAKYRTGNGNFEAENIDPFLCTHISYSFFGIDGASGRFKSLDTWLDMDTGLGMIRKTMQLKSKNPNLKILAVVGGWNEGSDKFSAMAADPHKRKAFIDSSLAFIKQYGFDGLDIDWEYPAQREGSSPRDKQNFVTLLKELKNALSPLNLELGIAVGASATTAAISYDIPNIAKYVDFINVMTYDFHNQATLSYNSPLKGQGENNVESAIKYWLNAGAPASKLIMGLAFYGRHFAYAQQPQAGAPQLGEGTPGPYTQQRGFLGYNEICQLKNSGYNFQFDNAHGVPYAYNGNQWIGFDDAKSIAMKVQLANTLNLGGAMVWSLESDDFRGECGEKYVLLNALNSALGGSSSWNPNPPQTVTTRKPSVVVTSAPVVSKPNAPAGCSSDGYFANQSDCNRFYQCSGGVRYEYNCAAGLHFDTVSLSCTWPGQANCGN

  3. Mary

    Hi Jing–

    I’m assuming you want this amino acid sequence analyzed for domains? You need to take it over to the SMART site and paste it right into their text box.

    We don’t host any of the analysis software here. We only host the training materials :)

  4. Pingback: Tip of the Week: A year’s worth of tips | The OpenHelix Blog

  5. Mary Post author

    Hi Anon–

    I’m assuming that’s a protein sequence….You need to take it over to SMART and enter it in the box that says Sequence.

    I just realized in our blog migration the movie didn’t make it. I’ll try to get that fixed.

Comments are closed.