I am so behind in my reading lately, but I have several flights coming up so usually I get a lot of reading done then :) And there’s an important issue of Bioinformatics that I’ve been meaning to get to. I wish I had read some of it yet and had more insight, but right now you’ll have to go over for yourself and check out the articles.
It is a whole issue devoted to next-gen sequencing. You may not need to know or use every algorithm over there, but I’m sure there will be some excellent overviews and diagrams that can help you think about the issues in this field.
You are going to be seeing this data soon if you haven’t already.