What’s the Answer? (visualizing gene fusions)

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In my ongoing quest for good visualization tools, a new question came up about a feature I haven’t seen available before. Does anyone know of a way to do this?

How to visualize gene fusions to better illustrate the gene structure?

I would like to visualize gene fusions in a way that illustrates the gene structure (primarily exons) of belonging to the normal gene partners and how they are joined to form the fusion (similar to the figure below). For a few events, I could draw this manually, but I’d like to create figures for hundreds of fusion events. Are there free or commercial tools available for this? I know people have typically visualized fusion events in IGV or using circos plots (e.g. FusionAnalyser), but this is not exactly what I’m looking for. Thanks.

[original post has image of the goal]

kendric.wang

There’s one answer with a tool I want to explore, gff2ps, but there’s room for additional suggestions. Go over and offer your ideas.