What’s the answer? (Drug databases)

BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of thecommunity and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those questions and answers here in this thread. You can ask questions in this thread, or you can always join in at BioStar.

This week’s highlighted question:

Drug-Drug Protein Target Database

Hello all. I have a list of genes identified in a HiSeq sequencing run that are related to cancer. I would like to cross this list with a database of known drug-drug target interactions so that if a drug is known( but not necessarily approved) to target a particular gene (protein) I can identify it. Does anyone know the best way to go about doing this. Ie… what is the best database or resource for this? Any help would be greatly appreciated!


One answer is very highly rated–becauseĀ malachig has a HUGE list of possible tools to use for Wayne’s purpose. Go have a look and see if you know these tools–or if there are others that might be suited as well. If you have other thoughts, please add them.