What’s the Answer? Lipid-binding protein database or tool?


BioStar is a site for asking, answering and discussing bioinformatics questions. We are members of the community and find it very useful. Often questions and answers arise at BioStar that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those questions and answers here in this thread. You can ask questions in this thread, or you can always join in at BioStar.

This week’s highlighted question:

How to identify the lipid binding region (amino acid residues) in the protein? Any specialized online/commercial tools is there.

The first answer starts off:

You can try CGDB - a database of membrane protein/lipid interactions. You can also try the predictive algorithm for lipid-binding sites using three-dimensional structural data, described by Scott, et al.

And then continues with more to read and some description. There is (at this time) another answer using PFAM.

3 thoughts on “What’s the Answer? Lipid-binding protein database or tool?

  1. Paul

    I found the following papers specialized in the search for (helical) lipid binding regions:

    Keller RCA (2011) The prediction of novel multiple lipid-binding regions in protein translocation motor proteins: a possible general feature. Cell Mol Biol Lett. 16(1):40-54.
    Keller RCA (2011) New user-friendly approach to obtain an eisenberg plot and its use as a practical tool in protein sequence analysis. Int J Mol Sci. 12(9):5577-91.

    Good luck!

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